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Hospital-acquired anemia found in 64% of 108 ICU patients at a southwest Florida hospital

A retrospective review of one southwest Florida ICU found a hemoglobin decline of 10% or more in 64% of patients. Their stays were longer on average.

Hospital-acquired anemia found in 64% of 108 ICU patients at a southwest Florida hospital
Photo: National Eye Institute, Wikimedia Commons, CC BY 2.0 · License: CC BY 2.0

Researchers reviewed medical records from the intensive care unit of a hospital in southwest Florida and found hospital-acquired anemia (HAA) in 69 of 108 adult patients (64%), according to a study in American Journal of Critical Care doi.orgAmerican Journal of Critical Caredoi.orgOpen source ↗. The retrospective, exploratory review used a 6-month convenience sample of 151 patients, of whom 108 met the inclusion criteria doi.orgAmerican Journal of Critical Caredoi.orgOpen source ↗. HAA was defined as a decline in hemoglobin of 10% or more from admission to discharge.

Hemoglobin decline and length of stay

The mean (SD) hemoglobin decline was 20% (8%) in patients with HAA and 4% (2%) in those without it (P < .001) doi.orgAmerican Journal of Critical Caredoi.orgOpen source ↗. Stays were longer for the 69 patients with HAA than for the 39 without: mean 5.9 (SD 5.8) days versus 3.3 (3.6) days (P = .005) doi.orgAmerican Journal of Critical Caredoi.orgOpen source ↗.

A sensitivity analysis excluded 6 outliers, leaving 102 patients. The difference persisted: 5.1 (4.2) days with HAA versus 2.8 (1.7) days without (P < .001) doi.orgAmerican Journal of Critical Caredoi.orgOpen source ↗.

Possible causes and limits

The authors name phlebotomy, intravenous fluid resuscitation and medications as contributing factors to HAA in intensive care units doi.orgAmerican Journal of Critical Caredoi.orgOpen source ↗. In this study, causality regarding phlebotomy was not directly measured doi.orgAmerican Journal of Critical Caredoi.orgOpen source ↗. The work is a retrospective record review in one unit, so it describes a correlation between hemoglobin decline and longer stays.

The authors concluded that the high prevalence of HAA supports implementing blood conservation strategies to improve clinical outcomes and reduce iatrogenic blood loss doi.orgAmerican Journal of Critical Caredoi.orgOpen source ↗.

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