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University of Utah identifies Lanmaoa asiatica behind Lilliputian hallucinations

Genetic analysis confirms a single bolete species triggers visions of tiny figures across Asia without known psychoactive compounds.

University of Utah identifies Lanmaoa asiatica behind Lilliputian hallucinations
Photo: attheu.utah.edu

Researchers at the University of Utah have confirmed that the bolete mushroom Lanmaoa asiatica causes vivid Lilliputian hallucinations across geographically separated communities in Southwest China and the northern Philippines, according to attheu.utah.edu attheu.utah.eduattheu.utah.eduattheu.utah.eduOpen source ↗. The findings, published in the journal Mycologia, reveal that the fungus lacks psilocybin or any other known psychoactive compounds, indicating the presence of an unidentified chemical agent.

Cross-regional genetic identification

Reports of miniature human hallucinations—figures typically measuring 3 to 30 centimeters tall—were documented in Papua New Guinea as early as 1934 under the term "mushroom madness". In 2024, doctoral researcher Colin Domnauer identified an indigenous community in the Northern Cordillera of the Philippines consuming a mushroom locally called "Sedesdem," which prompted the same symptoms as "Jian shou qing" in Yunnan, China.

Subsequent DNA sequencing confirmed that the specimens gathered from both countries belong exclusively to Lanmaoa asiatica. Prior to this survey, the species was believed to grow solely in Southwest China. Although dry conditions prevented specimen collection during field visits to Papua New Guinea, the verified identity across China and the Philippines demonstrates a unified biological origin rather than a purely cultural phenomenon.

Absence of known psychedelic pathways

Comprehensive genetic and chemical assessments of L. asiatica failed to detect canonical biosynthetic pathways for psilocybin, ibotenic acid, or other established mushroom toxins attheu.utah.eduattheu.utah.eduattheu.utah.eduOpen source ↗. The hallucinatory experiences reported by consumers consistently involve detailed entities dressed in colorful garments interacting with physical barriers and everyday objects in accord with classical physics.

To map the emergence of this trait, the research team sequenced 53 wild and fungarium specimens spanning the genus Lanmaoa, identifying 17 distinct species, four of which were previously undescribed. Comparative genomic screening established that L. asiatica is the only psychoactive member of the genus. The researchers intend to isolate the active molecule to investigate mechanisms underlying perceptual disorders, alcohol withdrawal, and degenerative conditions associated with Lilliputian hallucinations.

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