# Reneurx in knee osteoarthritis: 76% of patients halve pain at six months vs 46.3% on steroids

- Published: 2026-11-08 23:06 UTC
- Section: Life & Health › Medicine
- Tags: Reneurx, knee osteoarthritis, Brixton Biosciences, AAHKS Annual Meeting, pain reduction, responder rate, clinical study 264 patients
- URL: https://realtech.media/news/rt-682e5174e3344729ffe2d95f_reneurx_in_knee/

**In a 264-patient clinical study presented at the AAHKS meeting, Brixton Biosciences' Reneurx was compared with intra-articular corticosteroid injections over six months.**

![Reneurx in knee osteoarthritis: 76% of patients halve pain at six months vs 46.3% on steroids](https://realtech.media/media/2026/11/4d14c10f88ee49b1.webp)
*ad-hoc-news.de*

Comparative data on Reneurx therapy from the developer Brixton Biosciences were presented at the AAHKS Annual Meeting of the American Association of Hip and Knee Surgeons. According to ad-hoc-news.de, which cites a healio.com report of 6 November 2026, the work by Higgs M et al. (Paper 5) compared the procedure with conventional intra-articular corticosteroid injections in knee osteoarthritis [1]. Injections directly into the affected joint have long been a common part of orthopedic practice for chronic pain in this condition [1].

The clinical study included 264 adults with symptomatic knee osteoarthritis. They were treated at eleven specialized centers and followed for six months [1]. The authors focused on how lasting and pronounced the pain relief is with Reneurx compared with standard cortisone therapy [1].

## Pain reduction thresholds

For a pain reduction of at least 30 percent, 82.2 percent of participants in the Reneurx group reached the threshold after three months, versus 63.8 percent in the corticosteroid control group [1]. After six months the rate was 85.1 percent under Reneurx, while in the comparison group it fell to 61.3 percent [1].

A halving of pain (at least 50 percent) after six months was reported in 76 percent of Reneurx patients and in 46.3 percent of the corticosteroid group [1]. A reduction of 80 percent or more at six months was reached by 53.9 percent of participants under Reneurx and 26.3 percent under the standard injection [1].

## Subgroup with BMI of 30 or higher

One aspect of the analysis concerned patients with a body mass index of at least 30. In this subgroup, Reneurx showed a responder rate 23.9 percent higher than intra-articular corticosteroid injections [1].

The report notes that the relieving effect of steroid preparations in everyday clinical practice often fades after a few weeks, while the study followed patients over half a year [1]. The material does not give further details on the mechanism of Reneurx or on safety data.

## Sources

1. [ad-hoc-news.de](https://www.ad-hoc-news.de/wissenschaft/reneurx-bei-kniearthrose-76-prozent-halbieren-ihre-schmerzen-nach-sechs-monaten/70478092)

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Source: RealTech, realtech.media — https://realtech.media/news/rt-682e5174e3344729ffe2d95f_reneurx_in_knee/